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PCYT1A Rabbit pAb
PCYT1A Rabbit pAb
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- BACKGROUND
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P49585 |
| Reactivity | Rat, Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 42 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human PCYT1A |
| Epitope Specificity | 201-300/367 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasm; cytosol. Membrane. It can interconvert between an inactive cytosolic form and an active membrane-bound form. |
| SIMILARITY | Belongs to the cytidylyltransferase family. |
| SUBUNIT | Homodimer. |
| Post-translational modifications | The serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 5130 |
|---|---|
| Other Names | Choline-phosphate cytidylyltransferase A, 2.7.7.15, CCT-alpha, CTP:phosphocholine cytidylyltransferase A, CCT A, CT A, Phosphorylcholine transferase A, PCYT1A, CTPCT, PCYT1 |
| Target/Specificity | Cancer,Neurotrophins,Lipid metabolism |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | PCYT1A |
|---|---|
| Synonyms | CTPCT, PCYT1 |
| Function | Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. |
| Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:P19836}. Membrane {ECO:0000250|UniProtKB:P19836}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19836}. Endoplasmic reticulum membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:P19836}. Nucleus Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form. {ECO:0000250|UniProtKB:P19836} |
| Tissue Location | Brain, placenta, liver, fetal and adult lung. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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If you have any additional inquiries please email technical services at tech@abcepta.com.
Cat# AP94840
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